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. 2017 Oct 13;12:7469–7482. doi: 10.2147/IJN.S139775

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© 2017 Cai et al. This work is published and licensed by Dove Medical Press Limited

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Safety evaluation of Asp⁸-PU in vivo.

Notes: (A) Hemagglutination assay of mouse blood cells incubated with PU or Asp⁸-PU for 1 hour (bars 50 μm); (B) quantification of serum CK-MB, ALT, and BUN levels by clinical chemistry analysis (data shown as means ± SE, n=5 per group); (C) H&E images of heart, liver, spleen, and kidney collected from mouse tail vein injected with PU or Asp⁸-PU (bars 20 μm); (D) quantification analysis of serum TNFα, IFNγ, IL2, and IL6 by enzyme-linked immunosorbent assay.

Abbreviations: PU, polyurethane; BUN, blood urea nitrogen; ALT, alanine aminotransferase; H&E, hematoxylin-eosin; CK-MB, creatine kinase isoenzyme; BUN, blood urea nitrogen.

Safety evaluation of Asp⁸-PU in vivo.

Notes: (A) Hemagglutination assay of mouse blood cells incubated with PU or Asp⁸-PU for 1 hour (bars 50 μm); (B) quantification of serum CK-MB, ALT, and BUN levels by clinical chemistry analysis (data shown as means ± SE, n=5 per group); (C) H&E images of heart, liver, spleen, and kidney collected from mouse tail vein injected with PU or Asp⁸-PU (bars 20 μm); (D) quantification analysis of serum TNFα, IFNγ, IL2, and IL6 by enzyme-linked immunosorbent assay.

Abbreviations: PU, polyurethane; BUN, blood urea nitrogen; ALT, alanine aminotransferase; H&E, hematoxylin-eosin; CK-MB, creatine kinase isoenzyme; BUN, blood urea nitrogen.