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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Immunol Lett. 2017 Oct 3;191:47–54. doi: 10.1016/j.imlet.2017.08.024

Figure 4.

Figure 4

Endogenous td-TGF-β modulates tumor growth via modification of anti-tumor adaptive immunity.

An accelerated growth curve was observed in immunodeficient BALB/c nude mice implanted with CT26-TGF-β-R compared to control CT26-neo, revealing the impact of tumor-derived TGF-β on anti-tumor immunity. CT26-neo or CT26-TGF-β-R were implanted (106/mouse) in the right flank of nude mice (n=5 per group). The tumor growth curve measured by tumor volume at each indicated time point post tumor implantation is shown. * P<0.05.