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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Immunol Lett. 2017 Oct 3;191:47–54. doi: 10.1016/j.imlet.2017.08.024

Figure 6.

Figure 6

Excess td-TGF-β modulates tumor growth independently of adaptive immune function.

A similar early tumor establishment without progression was observed in immunodeficient nude mice implanted with CT26-TGF-β compared to control CT26-neo, confirming that the failure of CT26-TGF-β progression is not due to anti-tumor immunity, but rather likely suppression of tumor growth by TGF-β. CT26-neo or CT26-TGF-β were implanted (106/mouse) in the right flank of nude mice (n=5 per group). The tumor growth curve measured by tumor volume at each indicated time point post tumor implantation is shown. * P<0.05.