Table 2.
Distribution Frequencies for NFKB1 Promoter –94 del/ins ATTG and NFKB1A -826 C/T Genotypes in Controls and Patients.
| Variable | Controls (n=312) | Patients (n=312) | OR (95% CI) | p value | AOR (95% CI) | p value |
|---|---|---|---|---|---|---|
| NFKB1 Genotype | ||||||
| del/del | 22 (7.05%) | 18 (5.77%) | 1 (ref) | 1 (ref) | ||
| del/ins | 146 (46.79%) | 162 (51.92%) | 1.35 (0.69-2.62) | 0.367 | 2.36 (1.06-5.23) | 0.034 |
| ins/ins | 144 (46.15%) | 132 (42.31%) | 1.12 (0.57-2.18) | 0.738 | 1.75 (0.79-3.89) | 0.164 |
| del/ins+ins/ins | 290 (92.95%) | 294 (94.23%) | 1.23 (0.65-2.35) | 0.514 | 2.04 (0.94-4.41) | 0.068 |
| NFKB1A Genotype | ||||||
| CC | 16 (5.13%) | 32 (10.26%) | 1 (ref) | 1 (ref) | ||
| CT | 208 (66.67%) | 199 (63.78%) | 0.47 (0.25-0.89) | 0.022 | 0.47 (0.22-0.98) | 0.046 |
| TT | 88 (28.21%) | 81 (25.96%) | 0.46 (0.23-0.90) | 0.024 | 0.42 (0.19-0.92) | 0.031 |
| CT+TT | 296 (94.87%) | 280 (89.94%) | 0.47 (0.25-0.88) | 0.018 | 0.46 (0.22-0.94) | 0.034 |
OR, Odd Ratios; AOR, Adjusted Odd Ratios; ORs with 95% CIs were estimated by logistic regression models; AORs with 95% CIs were estimated by multiple logistic regression models after controlling for sex, age, tobacco chewing, alcohol consumption, and smoking status.