Table 8.

Results of the human and mouse case study

Test data set
Model	GRCh37	GRCh38	GRCm38
Radial using GRCh37, GRCm38 and first ORF
Sensitivity	9 8 . 8 6 %	9 9 . 4 2 %	98.51%
Specificity	97.56%	9 7 . 6 9 %	97.54%
Accuracy	9 8 . 2 1 %	9 8 . 5 5 %	98.02%
Radial using GRCh37, GRCm38 and longest ORF
Sensitivity	98.05%	98.67%	97.60%
Specificity	97.53%	97.59%	97.54%
Accuracy	97.79%	98.13%	97.57%
Radial using GRCh38, GRCm38 and first ORF
Sensitivity	91.22%	99.24%	9 8 . 6 6 %
Specificity	9 8 , 6 5 %	97.46%	97.41%
Accuracy	94.93%	98.35%	9 8 . 0 3 %
Radial using GRCh38, GRCm38 and longest ORF
Sensitivity	98.31%	98.20%	98.23%
Specificity	97.83%	97.63%	9 7 . 7 4 %
Accuracy	98.07%	97.91%	97.98%

We trained four models with two data sets, GRCh37/GRCm38 and GRCh38/GRCm38, and also compared the selection of two attributes, first and longest ORF relative lengths. The best results for each test data set, GRCh37, GRCh38 and GRCm38, are in bold