Table 1.

Chromosomal regions predicted to harbor lethal haplotypes identified in the analysis of the BovineSNP50 data

Chr	Haplotype Start – End Coordinates (bp)	Length (Mb)	Haplotype Frequencya	Number of Patriosb	Probabilityc	Sequenced Carriers	Concordant Variants	Concordant In High Coverage
1	27,786,985–29,095,768	1.3	0.023	39	0.0042	1	4	4
4	82,467,969–83,996,686	1.5	0.076	127	2.66E-09	21	9	118
8	62,040,920–63,000,189	1.0	0.023	35	0.0074	5	1	1
12	59,989,293–61,258,655	1.2	0.032	46	0.0014	12	0	0
15	82,317,986–83,144,172	0.8	0.038	31	0.011	10	1	1
17	46,514,063–47,462,424	1.0	0.045	49	0.00076	15	2	2
29	43,043,207–44,243,444	1.2	0.044	118	3.22E-08	16	3	13

^aHaplotypes estimated for 20 contiguous SNP loci

^bNumber of families out of 2480 for which the sire and maternal grandsire were both heterozygotes for the haplotype

^cProbability of observing no homozygous progeny if the haplotype is selectively neutral