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. 2017 Oct 18;17:93. doi: 10.1186/s12935-017-0464-0

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — AVN-C treatment activates caspases 3/7. a Representative sample of flow cytometric analysis of cells treated with CellEvent Caspase-3/7 Green Flow Cytometric Assay Kit to detect caspase activity (Comp-FL1-A) and dead cells (Comp-FL3-A) after treatment with DMSO 0.4% (vehicle), AVN-A, B, C at 400 µM, or STS for 96 h. b Graphical representation of the percentage of cells in each quadrant after staining. Results are a biological replicate done in triplicate. * Indicates statistical significance difference from 0.4% DMSO negative control for each individual quadrant as determined by a t test at p < 0.05 level of significance, ** indicates significance level at p < 0.01, *** indicates significance at p < 0.001 level