Table 5.

Associations between the CVH score (per 1- unit increase) and number of the subclinical disease markers stratified by gender

	Overall		Female		Male
	OR (95% CI)	P Value	OR (95% CI)	P Value	OR (95% CI)	P Value
≥1 vs. 0
Model 1	0.745 (0.704–0.788)	<0.001	0.533 (0.471–0.602)	<0.001	0.856 (0.797–0.902)	<0.001
Model 2	0.802 (0.749–0.858)	<0.001	0.676 (0.591–0.774)	<0.001	0.857 (0.791–0.928)	<0.001
Model 3	0.808 (0.755–0.865)	<0.001	0.682 (0.596–0.781)	<0.001	0.862 (0.796–0.933)	<0.001
≥2 vs. 0 or 1
Model 1	0.703 (0.644–0.767)	<0.001	0.509 (0.423–0.613)	<0.001	0.742 (0.657–0.838)	<0.001
Model 2	0.724 (0.654–0.802)	<0.001	0.627 (0.513–0.766)	<0.001	0.744 (0.658–0.840)	<0.001
Model 3	0.729 (0.658–0.807)	<0.001	0.640 (0.523–0.782)	0.001	0.781 (0.700–0.872)	<0.001
≥3 vs. 0, 1, or 2
Model 1	0.594 (0.463–0.761)	<0.001	0.465 (0.298–0.698)	<0.001	0.573 (0.422–0.778)	<0.001
Model 2	0.595 (0.464–0.763)	<0.001	0.568 (0.358–0.901)	0.016	0.579 (0.274–0.784)	<0.001
Model 3	0.603 (0.484–0.752)	<0.001	0.583 (0.368–0.925)	0.022	0.623 (0.468–0.830)	0.001

Values represent odds ratios (ORs) (95% confidence interval [CI]) per 1-unit increase in cardiovascular health (CVH) score; ≥ 1 denotes the presence of at least 1

component of increased carotid intima-media thickness, presence of carotid plaque, left ventricular hypertrophy (by ECG or echocardiography), left ventricular systolic dysfunction, or a reduced ankle-brachial index

Model 1, unadjusted; model 2, adjusted for age and sex; model 3, adjusted for age, sex and level of education