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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Nat Chem. 2017 Jan 30;9(7):667–675. doi: 10.1038/nchem.2706

Figure 1. Structure of anion transporters and their activity.

Figure 1

a, Structures of previously reported anion transporters 1 and 2. b, Structures of squaramide-based anion transporters 3–8 and the initial rate of chloride transport mediated by 1 mol% transporter from liposomes filled with a buffered NaCl solution and submerged in a buffered NaNO3 solution (kini), calculated Vs,max values, and IC50 values towards HeLa cells. Inset: relative activity (from high to low) for the various transporters in different assays.