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. Author manuscript; available in PMC: 2017 Dec 19.
Published in final edited form as: Oncogene. 2017 Jun 19;36(42):5840–5851. doi: 10.1038/onc.2017.171

Figure 3. EOC individual cells and MCAs exhibit distinct rates of lateral motility.

Figure 3

DOV13-GFP (Ncad+) and OvCa433-RFP (Ecad+) individual cells or MCAs were applied on top of a 3D collagen gel construct (1.5mg/ml) inside a glass-bottom dish; 8-hour time-lapse confocal imaging of cell/MCAs (green or red) and collagen matrix (blue) was performed in fluorescent and reflectance modes, respectively. A) Representative images of DOV13-GFP and OvCa433-RFP MCA dynamics are shown at stated time points (scale bars as indicated). B) Evaluation of lateral motility for different cell types (Mean±SD); all assays were repeated in triplicate; statistical significance shown between the lateral motilities of each cell line and fluorescent beads; p<0.05, Mann-Whitney U test.