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Paclitaxel increases transient sodium currents in dissociated human DRG neurons. (A) Traces of transient Na+ currents in small hDRG neurons with diameters <50 μm. Note that the current was greater after paclitaxel treatment (1 μmol/L, 24 h). (B) Quantification of the Na+ current amplitude. *P < 0.05, unpaired Student’s t-test, n = 29 neurons from 3 DRGs/3 donors. All data are expressed as mean ± SEM.
