TABLE 3.
Possible baseline risk factors for IC in clinical episodesa
| Variable | Value(s) |
P value | ||
|---|---|---|---|---|
| All episodes (n = 159) | IC episodes (n = 9) | Non-IC episodes (n = 150) | ||
| Mean age when suspected of IC, days (range) | 19.7 (4–96) | 15 (4–37) | 20 (4–96) | 0.42 |
| Mean wt when suspected of IC, g (range) | 1,010.7 (465–1,740) | 902.2 (500–1,740) | 1,017.4 (465–1,640) | 0.98 |
| Mean age of the commencement of breastfeeding, days (range) | 3 (0–11) | 4.2 (2–9) | 2.9 (0–11) | 0.67 |
| Mean age of the commencement of enteral nutrition, days (range) | 2.4 (0–13) | 3.4 (1–8) | 2.4 (0–13) | 0.49 |
| Received parenteral nutrition in the previous 15 days, % | 90.4 | 100 | 89.8 | 0.39 |
| Mean duration of parenteral nutrition, days (range) | 14.5 (1–432) | 11.4 (4–25) | 14.7 (1–432) | 0.70 |
| Received intravenous lipids in the previous 15 days, % | 87.2 | 88.9 | 87.1 | 0.67 |
| Mean duration of intravenous lipids, days (range) | 14.1 (1–408) | 11.1 (3–25) | 14.3 (1–408) | 0.76 |
| Received mechanical ventilation in the previous 48 h, % | 39 | 55.6 | 37.9 | 0.23 |
| Mean duration of mechanical ventilation, h (range) | 162.7 (5–960) | 39.4 (5–48) | 175 (8–960) | 0.02 |
| CPAP connection in the previous 48 h, % | 59 | 66.7 | 58.5 | 0.45 |
| Mean induration in CPAP, h (range) | 154 (5–999) | 101 (19–324) | 158.5 (5–999) | 0.30 |
| Central catheter in the previous 48 h, % | 63.5 | 66.7 | 63.3 | 0.57 |
| Mean duration with central catheter, h (range) | 152 (3–648) | 115 (48–168) | 154 (3–648) | 0.09 |
| Peripheral catheter in the previous 48 h, % | 48.4 | 66.7 | 47.3 | 0.21 |
| Mean duration with peripheral catheter, h (range) | 123 (8–720) | 106 (48–324) | 124 (8–720) | 0.40 |
| Prior surgery in the previous 15 days, % | 12.2 | 11.1 | 12.2 | 0.69 |
| Gastrointestinal surgery, % | 6.4 | 11.1 | 6.1 | 0.45 |
| Other surgeries, % | 6.4 | 0 | 6.8 | 0.60 |
| Prior Candida colonization, % | 5.2 (20.3% not done) | 44.4 (22.2% not done) | 2.8 (20.1% not done) | 0.000 |
| Candida dermatitis, % | 4.6 | 55.6 | 1.4 | 0.000 |
| Necrotizing enterocolitis, % | 13.5 | 22.2 | 13 | 0.16 |
| Antacids in the previous 15 days, % | 8.4 | 0 | 9 | 0.44 |
| Antibiotic in the previous 15 days, % | 79.5 | 77.8 | 79.6 | 0.58 |
| Prior antifungal, % | 39.6 | 44.4 | 39.3 | 0.51 |
a
CPAP, continuous positive airway pressure; IC, invasive candidiasis.