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. 2017 Oct 19;18(1):106. doi: 10.1186/s10194-017-0816-0

Table 2.

Red Flags for headache in pregnancy

1. Headache that peaks in severity in less than five minutes
2. New headache type versus a worsening of a previous headache
3. Change in previously stable headache pattern
4. Headache that changes with posture (e.g. Standing up)
5. Headache awakening the pregnant
6. Headache precipitated by physical activity or Valsalva manoeuvre (e.g. Coughing, laughing, straining)
7. Thrombophilia
8. Neurological symptoms or signs
9. Trauma
10. Fever
11. Seizures
12. History of malignancy
13. History of HIV or active infections
14. History of pituitary disorders
15. Elevated blood pressure
16. Recent travel at risk of infective disease

Modified from Mitsikostas et al. 2015 [38] (European Headache Federation consensus on technical investigation for primary headache disorders)