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. 2017 Oct 19;7:13612. doi: 10.1038/s41598-017-13497-8

Figure 6.

Figure 6

The effect of BMP4 is maintained across different NB and other neural cell lines. (a) Quantification and representative dot plots of the CD15/CD184 subpopulation in SH-SY5Y cells and the comparable CD15/CD184low subset in N-type, NMYC-amplified Kelly and BE(2)-M17 NB cell lines following 6 days of BMP4 treatment at a concentration of 100 ng/mL. (b) Similar effects on diminishing CD15 and CD184 surface antigen expression were also seen in non-transformed human embryonic stem cell derived neural stem cells (NSC) following treatment with 100ng/mL BMP4 for 3 days. Error bars indicate SD; **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001, unpaired Student’s t-test; n ≥ 3.