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. 2017 Oct 19;7:13534. doi: 10.1038/s41598-017-13903-1

Table 1.

Enrichment analysis for miR-200 networks inferred from control and tumour data.

miR-200 miR family Enrichment
Control Tumour
FDR FDR
Biological process Biological process
Cell adhesion 2.8480 × 10−4 Regulation of response to stimulus 1.6702 × 10−6
Biological adhesion 2.9344 × 10−4 Regulation of developmental process 1.6702 × 10−6
Cellular component movement 3.3965 × 10−6
Regulation of cell proliferation 3.3965 × 10−6
Regulation of immune system process 9.4147 × 10−6
Molecular function Molecular function
Transmembrane receptor protein 3.6305 × 10−5 Receptor binding 1.9975 × 10−6
kinase activity
Transmembrane receptor protein 9.7399 × 10−5 Carbohydrate binding 1.2562 × 10−5
tyrosine kinase activity
Protein tyrosine kinase activity 3.6087 × 10−3 Polysaccharide binding 6.1321 × 10−4
Protein kinase activity 1.0257 × 10−2 Pattern binding 6.1321 × 10−4
Growth factor binding 9.2541 × 10−4
Cellular component Cellular component
Cell junction 8.6796 × 10−13 E×tracellular region part 9.1753 × 10−9
Anchoring junction 6.3052 × 10−11 E×tracellular space 9.4147 × 10−6
Cell-cell junction 6.3052 × 10−11 E×tracellular matrix 3.3656 × 10−4
Adherens junction 1.0953 × 10−7 Cell surface 3.3656 × 10−4
Basolateral plasma membrane 1.0953 × 10−7 Proteinaceous extracellular matrix 5.0306 × 10−4
miR-199 Enrichment
Tumour FDR
Biological process
Biological adhesion 8.5209 × 10−29
Cell adhesion 8.5209 × 10−29
Extracellular structure organization 1.0724 × 10−13
Skeletal system development 3.9744 × 10−13
Extracellular matrix organization 1.9525 × 10−12
Molecular function
Calcium ion binding 1.1340 × 10−16
Extracellular matrix structural constituent 2.8499 × 10−11
Integrin binding 7.4108 × 10−9
Glycosaminoglycan binding 1.0312 × 10−6
Pattern binding 5.5217 × 10−6
Cellular component
Extracellular matrix 4.0521 × 10−42
Proteinaceous extracellular matrix 7.9803 × 10−41
Extracellular region part 1.2162 × 10−27
Calcium ion binding 1.1340 × 10−16
Extracellular matrix part 1.8404 × 10−13