Table 3.
HLA antibody characteristics of women with uneventful pregnancy in relation to gravidity and parity.
| Primigravidae (n = 28) | Primi-/multipara (n = 73) | P-value | |||
|---|---|---|---|---|---|
| Gestation week 11–13 | HLA class I and/or II positive | % | 30 | 67 | 0.003 |
| HLA class I positive | % | 26 | 53 | 0.03 | |
| HLA class II positive | % | 17 | 43 | 0.03 | |
| Percent positive beads per panel | median (IQR) | 0 (0–6) | 18 (0–43) | 0.003 | |
| MFImax | median (IQR) | 257 (182–331) | 2869 (2802–2936) | 0.011 | |
| Whole pregnancy | HLA class I and/or II positive | % | 68 | 88 | 0.02 |
| HLA class I positive | % | 61 | 77 | 0.11 | |
| HLA class II positive | % | 43 | 62 | 0.09 | |
| Percent positive beads per panel | median (IQR) | 0 (0–18) | 12 (0–64) | <0.001 | |
| MFImax | median (IQR) | 370 (277–1050) | 3073 (509–7370) | <0.001 | |
IQR, inter quartile range; MFImax, median fluorescence intensity of the highest ranked positive bead in the bead panel.