Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Oct 19;7:13544. doi: 10.1038/s41598-017-12881-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Blocking the formation of CD300b complexes enhances receptor signaling. (A) RBL-2H3 cells were stably transfected with HA-CD300b wt or HA-CD300b _E28A-Q29G. RBL-2H3 transfectants were transiently transfected with 3 × NFAT/AP1-Luciferase and TK-Renilla reporter plasmids. Luciferase activity was measured after stimulation for 7 h with the indicated antibodies. Data were normalized and expressed as a percentage of luciferase activity considering IgE stimulation as the top threshold of activation. Duplicates were performed for all stimulations. The result is a mean ± SD of three independent experiments. Group differences were investigated by unpaired, two-tail Student’s t test. p values are indicated for statistically different means: ** ≤ 0.01.