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. 2017 Oct 19;7:13584. doi: 10.1038/s41598-017-13194-6

Figure 4.

Figure 4

Labeling different collagen types in normal human donor, and keratoconus cornea. Striae were visible in collagen VI, lumican and keratocan (not shown). Stromal collagen fibrils that are made of collagen I and collagen V appear not to be involved in striae formation. Collagen VI presents a filamentous structure and it is involved in maintaining the interfibril space. Its density is increased at the level of striae. Arrowheads indicate striae. Scale bars show 50 µm.