Table 3.

Summary of estimated parameter values in the model.

Variable	Constraints	Parameter Value ($\mathit{\mu }$, $\mathit{\sigma }$)	Notes
Death condition	13	13	pre-defined (Detterbuck 2008)
Diameter, Stage I	>0.3 & <5	1.72, 4.70
Diameter, Stage II	>0.3	1.96, 1.63
Diameter, Stage IIIA	>0.3	1.91, 9.40
Diameter, Stage IIIB	>0.3	2.76, 6.87
Diameter, Stage IV	>0.3	3.86, 8.82
Growth parameter $\rho$	>0	7.00 × 10−5, 7.23 × 10−3	Decrease of growth rate
Carrying capacity	>0	30
Radiation cell kill $\alpha$	>0	0.0398, 0.168	$\alpha /\beta$ is 10 (Mehta 2001)
correlation	>0	0.87	(Lee 2016, Ishibashi 2017)
Chemo cell kill ${\beta }_c$	>0	0.028, 0.0007	Unit: per mg/m3