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Comparison of performance of serum HE4 and CA125 in the diagnosis of endometrial cancer.
| Item | Sensitivity (%) | Specificity (%) | Youden index | Coincidence rate (%) | NPV (%) | PPV (%) |
|---|---|---|---|---|---|---|
| HE4 | 57.2 | 95.8 | 0.518 | 79.8 | 76.5 | 89.6 |
| CA125 | 51.7 | 93.9 | 0.457 | 77.1 | 73.7 | 85.2 |
| HE4+CA125 | 73.2 | 91.2 | 0.641 | 83.5 | 83.4 | 84.8 |
NPV: Negative predictive value; PPV: Positive predictive value.
