Table-I.

The correlation between Topo IIα and Ki67 expression and clinical pathological characteristics.

Factor		N	Topo IIα			Ki67
			+	-	P	+	-	P
Age (years)	<50	53	25	28	0.837	38	15	0.326
	≥50	63	30	33		39	24
Tumor size (cm)	≤2	30	11	19	0.097	18	12	0.076
	>2, ≤5	71	41	30		53	18
	>5	15	5	10		6	9
Number of metastatic lymph glands	0	59	21	38	0.043	35	24	0.037
	≥1, <4	18	10	8		9	9
	≥4, <10	15	9	8		15	0
	≥10	24	18	6		19	5
PR	+	56	27	29	0.829	18	38	0.000
	-	60	31	29		27	33
ER	+	74	36	38	0.868	46	28	0.238
	-	42	21	21		31	11
HER-2	+	45	25	20	0.269	33	12	0.242
	-	71	31	40		44	27