TABLE 3.
Strain | Trimethoprim MIC (mg/liter) for the indicated strain on the following mediuma: |
|||||||
---|---|---|---|---|---|---|---|---|
BHI |
Human blood |
Sheep blood |
Horse blood |
|||||
−T | +T | −T | +T | −T | +T | −T | +T | |
Parent | 1 | >32 | 0.75 | >32 | >32 | >32 | 1 | >32 |
pabA mutant | 1 | >32 | >32 | >32 | >32 | >0.002 | >32 | |
tdk mutant | 0.25 | 0.25 | 0.75 | 0.75 | 0.5 | 0.5 | 1 | 1 |
−T, no exogenous thymidine added, +T, thymidine added at 400 μg ml−1.