FIG 2.

Effect of chronic-plus-binge alcohol administration on changes in the bone marrow granulocyte (Gr1⁺) population in mice challenged i.v. with saline or E. coli for 24 h. Control, i.p. saline to mice on control diet; Alcohol, acute alcohol intoxication to mice on chronic alcohol diet; Saline, i.v. saline; E. coli 1 × 10⁶, 1 × 10⁶ CFU E. coli/mouse i.v.; E. coli 5 × 10⁷, i.v. 5 × 10⁷ CFU E. coli/mouse. The data are presented as means and SEM; n = 5. Bars with different letters in each graph are statistically significantly different (P < 0.05).