FIG 1.
Brucella melitensis infection leads to increased numbers of lymphocytes and myeloid and granulocyte cells in the spleen. Wild-type C57BL/6 mice were infected intraperitoneally (i.p.) with a dose of 105 CFU of B. melitensis and sacrificed at the indicated times. The data represent the number of CFU per spleen (A) and the number of cells positive for the indicated cell markers (B) determined by combining the results of cell counting (using a Thoma cell counting chamber) and flow cytometry. These results are representative of at least two independent experiments (n = 8). Folli, follicular; infDC, inflammatory dendritic cells.