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. 2016 Oct 31;14(10):850–861. doi: 10.1038/cmi.2016.53

Figure 6.

Figure 6

Later-neutralized IL-17A significantly reduced IFN-γ production. Mice were neutralized of IL-17A production with or without depletion of γδ T cells in Cm-infected mice as described in the legend to Figure 5. Percentage of IFN-γ-producing CD4+ (a) and CD8+ (b) T cells in the lung tissues at day 13 p.i. were determined by intracellular cytokine staining as described in the Materials and Methods section. The absolute number of IFN-γ-producing CD4+ (c) and CD8+ (d) T cells in the lung tissues was calculated as described in the legend to Figure 2. Three independent experiments with four mice in each group were tested. The results are shown as the mean±s.d.; *P<0.05; **P<0.01; ***P<0.001.