Table 3.
Summary of Surgical Site Infection Clinical Outcome of PICO⋄ Single-Use Negative Pressure Wound Therapy Compared with Standard Care according to Surgical Indication
| Surgical procedure | Risk with PICO⋄ | Risk with standard care | Relative reduction | Number studies | Risk ratio (95% CI) | NNT |
|---|---|---|---|---|---|---|
| Orthopedic - Reconstruction | 4.2% | 10.5% | 60% | 5 | 0.48 (0.25 to 0.93) | 16 |
| Colorectal | 8.8% | 30.2% | 71% | 4 | 0.29 (0.15 to 0.57) | 5 |
| Cesarean section | 6.7% | 13.2% | 49% | 3 | 0.53 (0.33 to 0.84) | 15 |
| Abdominal (colorectal + C-section) | 7.2% | 16.4% | 56% | 7 | 0.44 (0.30 to 0.64) | 11 |
CI = confidence interval; NNT = number needed to treat.