Table 3.
A summary of effects of disopyramide and quinidine on 3D wedge simulations.
| DF (Hz) | Lifespan reentry (s) | DF (Hz) | Lifespan reentry (s) | ||
|---|---|---|---|---|---|
| SQT1 | 6.32 | 5.00 (NST = 0) |
SQT1 | 6.32 | 5.00 (NST = 0) |
| +1 μM DISO | 5.99 | 4.00 (NST = 2) |
+1 μM QUIN | 5.03 | 4.97 (NST = 1) |
| +2 μM DISO | 5.29 | 4.34 (NST = 2) |
+2 μM QUIN | 4.39 | 3.83 (NST = 3) |
| +5 μM DISO | 4.26 | 5.00 (NST = 0) |
+5 μM QUIN | 3.15 | 4.93 (NST = 1) |
The averaged dominant frequency (DF) and lifespan of re-entrant excitation waves (NST denotes number of non-sustained arrhythmias) in drug-free SQT1 conditions is shown, as well as upon application of different concentrations of disopyramide (DISO) and quinidine (QUIN). In all cases n = 6.