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. 2017 Sep 29;8:1225. doi: 10.3389/fimmu.2017.01225

Table 2.

Correlation of clinicopathological parameters with MPO and CD8 score according to different tumor compartments.

Parameter MPO stroma
MPO tumor
MPO total
CD8 stroma
CD8 tumor
CD8 total
Low, n (%) High, n (%) p-Value Low, n (%) High, n (%) p-Value Low, n (%) High, n (%) p-Value Low, n (%) High, n (%) p-Value Low, n (%) High, n (%) p-Value Low, n (%) High, n (%) p-Value
T-stage
T1/2 17 (68) 40 (74) 0.57 47 (69) 10 (91) 0.13 17 (71) 40 (73) 0.86 48 (70) 9 (90) 0.18 36 (67) 21 (84) 0.11 29 (66) 28 (80) 0.17
T3/4 8 (32) 14 (26) 21 (31) 1 (9) 7 (29) 15 (27) 21 (30) 1 (10) 18 (33) 4 (16) 15 (34) 7 (20)
N-stage
N0 15 (60) 34 (63) 0.8 42 (62) 7 (64) 0.9 14 (58) 35 (64) 0.65 41 (59) 8 (80) 0.21 30 (56) 19 (76) 0.08 24 (55) 25 (71) 0.12
N1 10 (40) 20 (37) 26 (38) 4 (36) 10 (42) 20 (36) 28 (41) 2 (20) 24 (44) 6 (24) 20 (45) 10 (29)
G
G1/2 15 (60) 38 (75) 0.2 44 (67) 9 (90) 0.13 14 (58) 39 (75) 0.14 46 (70) 7 (70) 0.98 33 (65) 20 (80) 0.17 26 (63) 27 (77) 0.19
G3 10 (40) 13 (25) 22 (33) 1 (10) 10 (42) 13 (25) 20 (30) 3 (30) 18 (35) 5 (20) 15 (37) 8 (23)
Gender
Male 10 (40) 24 (44) 0.7 26 (38) 8 (73) 0.03 9 (38) 25 (45) 0.51 32 (46) 2 (20) 0.12 23 (43) 11 (44) 0.91 20 (45) 14 (40) 0.63
Female 15 (60) 30 (56) 42 (62) 3 (27) 15 (62) 30 (55) 37 (54) 8 (8) 31 (57) 14 (56) 24 (55) 21 (60)
Age (years)
<58 13 (52) 25 (46) 0.64 30 (44) 8 (73) 0.08 12 (50) 26 (47) 0.82 34 (49) 4 (40) 0.58 26 (48) 12 (48) 0.99 23 (52) 15 (43) 0.4
≥58 12 (48) 29 (54) 38 (56) 3 (7) 12 (50) 29 (53) 35 (51) 6 (60) 28 (52) 13 (52) 21 (48) 20 (57)
CD8 stroma
Low 19 (76) 50 (93) 0.039 58 (85) 11 (100) 0.18 18 (75) 51 (93) 0.029
High 6 (24) 4 (7) 10 (15) 0 (0) 6 (25) 4 (7)
CD8 tumor
Low 16 (64) 38 (70) 0.57 46 (68) 8 (73) 0.74 15 (63) 39 (71) 0.46
High 9 (36) 16 (30) 22 (32) 3 (27) 9 (37) 16 (29)
CD8 total
Low 12 (48) 32 (59) 0.3.5 37 (54) 7 (64) 0.57 11 (46) 33 (60) 0.24
High 13 (52) 22 (41) 31 (46) 4 (36) 13 (54) 22 (40)

MPO, myeloperoxidase.

Significant values have been marked with bold.