Table 1.
1998 | 1999 | 2000 | 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | Significant for trend | ||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Non‐overdose cases | n | 134,098 | 136,807 | 146,778 | 154,100 | 156,476 | 164,046 | 170,767 | 176,669 | 177,707 | 172,177 | 159,440 | 159,266 | 163,367 | P < 0.0001 for number |
Age, years, mean (SD) | 48.3 ± 23.6 | 48.9 ± 24.1 | 49.1 ± 24.0 | 49.5 ± 24.2 | 50.1 ± 24.4 | 50.4 ± 24.7 | 51.2 ± 24.8 | 51.9 ± 24.9 | 52.1 ± 25.0 | 52.8 ± 25.1 | 53.7 ± 25.0 | 53.9 ± 25.4 | 55.3 ± 25.2 | P < 0.0001 for age | |
Median (IQR) | 51 (28–66) | 52 (29–68) | 52 (29–68) | 53 (29–69) | 54 (30–70) | 54 (30–70) | 55 (31–71) | 56 (31–72) | 57 (32–73) | 58 (32–74) | 59 (34–74) | 59 (34–75) | 61 (36–76) | ||
Age distribution, years | |||||||||||||||
0–15 | 12,132 | 12,574 | 12,973 | 13,600 | 14,098 | 14,943 | 15,049 | 15,319 | 15,105 | 14,577 | 12,944 | 13,997 | 12,918 | ||
(%) | (9.0) | (9.2) | (8.8) | (8.8) | (9.0) | (9.1) | (8.8) | (8.7) | (8.5) | (8.5) | (8.1) | (8.8) | (7.9) | ||
16–40 | 36,264 | 36,711 | 40,247 | 41,680 | 41,388 | 43,456 | 44,136 | 44,882 | 45,501 | 42,690 | 37,953 | 36,461 | 35,565 | ||
(%) | (27.0) | (26.8) | (27.4) | (27.0) | (26.5) | (26.5) | (25.8) | (25.4) | (25.6) | (24.8) | (23.8) | (22.9) | (21.8) | ||
41–65 | 50,523 | 48,856 | 51,444 | 52,643 | 51,671 | 51,695 | 52,574 | 52,700 | 52,229 | 48,955 | 44,579 | 43,317 | 43,741 | ||
(%) | (37.7) | (35.7) | (35.0) | (34.2) | (33.0) | (31.5) | (30.8) | (29.8) | (29.4) | (28.4) | (28.0) | (27.2) | (26.8) | ||
≥66 | 35,173 | 38,666 | 42,114 | 46,177 | 49,318 | 53,952 | 59,007 | 63,768 | 64,872 | 65,955 | 63,964 | 65,491 | 71,143 | ||
(%) | (26.2) | (28.3) | (28.7) | (30.0) | (31.5) | (32.9) | (34.6) | (36.1) | (36.5) | (38.3) | (40.1) | (41.1) | (43.5) | ||
Male, n | 82,664 | 83,150 | 88,522 | 92,153 | 92,380 | 95,774 | 97,940 | 100,006 | 99,167 | 95,723 | 88,174 | 88,111 | 89,110 | P < 0.0001 for sex | |
(%) | (61.7) | (60.8) | (60.4) | (59.9) | (59.1) | (58.4) | (57.4) | (56.7) | (55.8) | (55.6) | (55.3) | (55.3) | (54.6) | ||
Female, n | 51,264 | 53,522 | 58,134 | 61,805 | 63,949 | 68,162 | 72,701 | 76,559 | 78,409 | 76,337 | 71,266 | 71,155 | 74,257 | ||
(%) | (38.3) | (39.2) | (39.6) | (40.1) | (40.9) | (41.6) | (42.6) | (43.4) | (44.2) | (44.4) | (44.7) | (44.7) | (45.6) | ||
Overdose cases | n | 1,136 | 1,168 | 1,297 | 1,454 | 1,568 | 1,714 | 1,804 | 1,978 | 1,968 | 1,746 | 1,811 | 1,985 | 1,822 | P < 0.0001 for number |
Age, years, mean (SD) | 37.9 ± 16.5 | 38.5 ± 17.1 | 37.4 ± 16.4 | 37.0 ± 15.9 | 36.6 ± 16.0 | 36.1 ± 16.0 | 36.4 ± 15.8 | 35.5 ± 15.4 | 35.4 ± 15.6 | 36.1 ± 16.0 | 36.8 ± 16.4 | 37.5 ± 16.4 | 38.6 ± 17.1 | P = 0.52 for age | |
Median (IQR) | 34 (26–49) | 34 (26–50) | 33 (26–48) | 34 (26–47) | 33 (25–45) | 33 (25–45) | 34 (25–45) | 32 (25–43) | 33 (24–42) | 33 (24–43) | 34 (24–45) | 34 (25–46) | 35 (26–47) | ||
Age distribution, years | |||||||||||||||
0–15 | 40 | 29 | 35 | 35 | 40 | 52 | 53 | 57 | 55 | 44 | 41 | 44 | 47 | ||
(%) | (3.5) | (2.5) | (2.7) | (2.4) | (2.6) | (3.0) | (2.9) | (2.9) | (2.8) | (2.5) | (2.3) | (2.2) | (2.6) | ||
16–40 | 667 | 709 | 814 | 939 | 1,012 | 1,119 | 1,187 | 1,345 | 1,345 | 1,165 | 1,170 | 1,255 | 1,084 | ||
(%) | (58.7) | (60.7) | (62.8) | (64.6) | (64.5) | (65.3) | (65.8) | (68.0) | (68.3) | (66.7) | (64.6) | (63.2) | (59.5) | ||
41–65 | 340 | 326 | 356 | 384 | 405 | 437 | 456 | 475 | 446 | 421 | 466 | 536 | 514 | ||
(%) | (29.9) | (27.9) | (27.4) | (26.4) | (25.8) | (25.5) | (25.3) | (24.0) | (22.7) | (24.1) | (25.7) | (27.0) | (28.2) | ||
≥66 | 89 | 104 | 92 | 96 | 111 | 106 | 108 | 101 | 122 | 116 | 134 | 150 | 177 | ||
(%) | (7.8) | (8.9) | (7.1) | (6.6) | (7.1) | (6.2) | (6.0) | (5.1) | (6.2) | (6.6) | (7.4) | (7.6) | (9.7) | ||
Male, n | 369 | 392 | 448 | 479 | 487 | 541 | 516 | 557 | 501 | 465 | 489 | 611 | 541 | P < 0.0001 for sex | |
(%) | (32.5) | (33.6) | (34.5) | (32.9) | (31.1) | (31.6) | (28.6) | (28.2) | (25.5) | (26.6) | (27.0) | (30.8) | (29.7) | ||
Female, n | 767 | 776 | 849 | 975 | 1,081 | 1,173 | 1,288 | 1,421 | 1,467 | 1,281 | 1,322 | 1,374 | 1,281 | ||
(%) | (67.5) | (66.4) | (65.5) | (67.1) | (68.9) | (68.4) | (71.4) | (71.8) | (74.5) | (73.4) | (73.0) | (69.2) | (70.3) |
IQR, interquartile range.