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. 2017 Sep;12(9):1479–1484. doi: 10.4103/1673-5374.215260

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Copyright: © Neural Regeneration Research

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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Changes in p-tau and tau protein expression levels in the hippocampus of AD rats under GS treatment.

(A, B) p-tau and tau protein expression in the hippocampus of AD rats under GS treatment. Results are the gray value ratio of target proteins and β-actin. *P < 0.01, vs. sham group; #P < 0.01, vs. AD group. Data are shown as the mean ± SD (n = 3, one-way analysis of variance and the least significant difference test). Sham: Sham-operated group (injected with normal saline, normal feed); AD: Alzheimer's disease group (intraperitoneal injection of D-galactose in combination with bilateral hippocampal injection of amyloid-β peptide (25–35), 0.5% sodium carboxymethyl cellulose); GS: genistein group (90 mg/kg GS); EV: estradiol valerate group (0.3 mg/kg EV). p-tau: Phosphorylated tau protein.