Table 1.

Syndromes with associated congenital fibrosis

Disorder	Clinical features
Ivemark syndrome	Asplenia, heart malformations, abnormal lung lobation, localized renal dysplasia
Jeune syndrome	Small, narrow chest, shortened bones of the arms and legs, extra fingers and/or toes, renal dysfunction
Joubert syndrome	Cerebellar vermis hypoplasia, retinitis pigmentosa, ataxia
Bardet-Biedl syndrome	Retinitis pigmentosa, polydactyly, mental retardation, hypogonadism, renal dysfunction
Meckel-Gruber syndrome	Renal cystic disease, microcephaly, hypoplastic genitalia, congenital heart disease, polydactyly
Arima syndrome	Cerebellar vermis hypoplasia, renal abnormalities, psychomotor retardation