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. 2017 Aug 25;14(4):4625–4632. doi: 10.3892/ol.2017.6825

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Copyright: © Zhou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 8. — Overexpression of HOXB4 enhanced doxorubicin-mediated downregulation of cell apoptosis in breast cancer cells. (A-C) Apoptosis assays was assessed in MCF-7, MCF-10Aand MDA-MB-231 cells with or without HOXB4 overexpression. (D) Bcl-2 and Bax protein levels were determined by western blotting in MCF-7 cells treated with Lenti-HOXB4-CDS with or without doxorubicin. (E) Bcl-2 and Bax protein levels were determined by western blotting in MCF-7 cells with or without HOXB4 knockdown. Data are presented as means ± SD. n=3, *P<0.05, **P<0.01.