. 2017 Aug 14;14(4):4467–4476. doi: 10.3892/ol.2017.6752

Table IV.

Correlation analyses of clinical parameters and immunohistochemical staining parameters.

Clinical parameter	Statistic	Age	Histology	pT	pN	pM	Grade	FIGO	E6	p53-mutated	MDM2	Galectin-3
Age (years)	Correlation coefficient	−.019	.004	−.115	−.065	−.140*	.354^b	.133^a	.169^b	.107	.026	.050
	Sig. (2-tailed)	.766	.945	.070	.307	.028	.000	.037	.008	.095	.686	.438
	N	250	250	250	250	246	250	245	244	246	241	240
Histology	Correlation coefficient	.028	1.000	.000	−.073	−.108	−.084	.045	.156^a	−.162^a	.075	.029
	Sig. (2-tailed)	.664	.	.994	.249	.089	.185	.477	.015	.010	.242	.652
	N	245	249	249	249	249	249	249	245	249	244	243
pT	Correlation coefficient	.276^b	.000	1.000	.359^b	−.202^b	.182^b	.380^b	.174^b	.055	−.019	−.039
	Sig. (2-tailed)	.000	.994	.	.000	.001	.004	.000	.006	.384	.762	.540
	N	246	249	250	250	250	250	250	246	250	245	244
pN	Correlation coefficient	.037	−.073	.359^b	1.000	−.172^b	.212^b	.240^b	.033	−.050	−.058	−.033
	Sig. (2-tailed)	.559	.249	.000	.	.007	.001	.000	.610	.435	.370	.608
	N	246	249	250	250	250	250	250	246	250	245	244
pM	Correlation coefficient	−.081	−.108	−.202^b	−.172^b	1.000	−.146*	−.150^a	−.037	.004	.032	−.074
	Sig. (2-tailed)	.206	.089	.001	.007	.	.021	.018	.560	.951	.619	.252
	N	246	249	250	250	250	250	250	246	250	245	244
Grade	Correlation coefficient	−.081	−.084	.182^b	.212^b	−.146^a	1.000	.093	.084	−.065	−.175^b	−.047
	Sig. (2-tailed)	.203	.185	.004	.001	.021	.	.142	.191	.302	.006	.461
	N	246	249	250	250	250	250	250	246	250	245	244
FIGO	Correlation coefficient	.076	.045	.380^b	.240^b	−.150^a	.093	1.000	.227^b	−.099	.021	.067
	Sig. (2-tailed)	.233	.477	.000	.000	.018	.142	.	.000	.120	.748	.296
	N	246	249	250	250	250	250	250	246	250	245	244
E6	Correlation coefficient	.088	.156^a	.174^b	.033	−.037	.084	.227^b	1.000	.093	.001	.009
	Sig. (2-tailed)	.173	.015	.006	.610	.560	.191	.000	.	.147	.986	.893
	N	242	245	246	246	246	246	246	246	246	244	243
p53-mutated	Correlation coefficient	.092	−.290^b	.016	−.019	.004	−.115	−.065	−.140^a	1.000	.133^a	.169^b
	Sig. (2-tailed)	.148	.000	.796	.766	.945	.070	.307	.028	.	.037	.008
	N	246	249	250	250	250	250	250	246	250	245	244
MDM2	Correlation coefficient	.026	.075	−.019	−.058	.032	−.175^b	.021	.001	−.042	1.000	.181^b
	Sig. (2-tailed)	.686	.242	.762	.370	.619	.006	.748	.986	.511	.	.005
	N	241	244	245	245	245	245	245	244	245	245	243
Galectin-3	Correlation coefficient	.050	.029	−.039	−.033	−.074	−.047	.067	.009	−.020	.181^b	1.000
	Sig. (2-tailed)	.438	.652	.540	.608	.252	.461	.296	.893	.760	.005	.
	N	240	243	244	244	244	244	244	243	244	243	244

P<0.05

P<0.01. pT, pathological tumour stage; pN, pathological node stage; pM, pathological metastasis stage; FIGO, International Federation of Gynecology and Obstetrics stage; MDM2, MDM2 proto-oncogene.