Table II.
Association between the expression of NCCRP1 mRNA and clinicopathological parameters of 213 patients with squamous cell carcinoma of the esophagus.
| Parameters | Low NCCRP1 expression (n) | High NCCRP1 expression (n) | P-value |
|---|---|---|---|
| Age (years) | |||
| <65 | 47 | 46 | |
| ≥65 | 59 | 61 | 0.843 |
| Sex | |||
| Male | 87 | 80 | |
| Female | 19 | 27 | 0.194 |
| Preoperative symptoms | |||
| Absent | 24 | 29 | |
| Present | 82 | 78 | 0.451 |
| Brinkman index | |||
| <1,000 | 66 | 75 | |
| ≥1,000 | 40 | 32 | 0.227 |
| Excessive alcohol consumption | |||
| Absent | 30 | 29 | |
| Present | 76 | 78 | 0.845 |
| Carcinoembryonic antigen (ng/ml) | |||
| ≤5 | 94 | 96 | |
| >5 | 12 | 11 | 0.807 |
| SCC (ng/ml) | |||
| ≤1.5 | 65 | 68 | |
| >1.5 | 41 | 39 | 0.737 |
| Tumor size (cm) | |||
| <5.0 | 63 | 62 | |
| ≥5.0 | 43 | 45 | 0.825 |
| Tumor location | |||
| Ce, Mt | 65 | 68 | |
| Lt, Ae | 41 | 39 | 0.737 |
| UICC pT factor | |||
| pT1-2 | 39 | 42 | |
| T3-4 | 67 | 65 | 0.712 |
| Differentiation | |||
| Moderate to well | 90 | 94 | |
| Poor | 16 | 13 | 0.531 |
| Lymphatic involvement | |||
| Absent | 30 | 28 | |
| Present | 76 | 79 | 0.727 |
| Vessel invasion | |||
| Absent | 62 | 68 | |
| Present | 44 | 39 | 0.449 |
| Intraepithelial spread | |||
| Absent | 79 | 82 | |
| Present | 27 | 25 | 0.720 |
| Intramural metastasis | |||
| Absent | 100 | 97 | |
| Present | 6 | 10 | 0.305 |
| Lymph node metastasis | |||
| Absent | 37 | 44 | |
| Present | 69 | 63 | 0.350 |
χ2 test. Statistical significance (P<0.05). SCC, squamous cell carcinoma-related antigen; UICC, Union for International Cancer Control.