Table II.
Correlation between miR-214 status detected by ISH in pancreatic ductal adenocarcinoma tissues and clinicopathological features.
| miR-214 ISH staining | ||||
|---|---|---|---|---|
| Clinicopathological feature | Negative (n=9) | Positive (n)=34 | rs | P-value |
| Sex | 0.102 | 0.4900000 | ||
| Male | 4 | 15 | ||
| Female | 5 | 19 | ||
| Tumor size, cm | 1.882±0.24 | 3.118±0.52 | 0.601 | 0.0000008 |
| Histological grade | 0.407 | 0.0000015 | ||
| G1 | 5 | 4 | ||
| G2 | 3 | 17 | ||
| G3 | 1 | 13 | ||
| LN metastasis | 0.532 | 0.0000001 | ||
| N0 | 7 | 6 | ||
| N1 | 2 | 28 | ||
| pTNM stage | 0.327 | 0.000042 | ||
| I–II | 7 | 5 | ||
| III | 2 | 16 | ||
| IV | 0 | 13 | ||
Tumor size data are expressed as mean. P-values were calculated by Spearman's rank correlation test (n=43). ISH, in situ hybridization; miR, microRNA; TNM, tumor node metastasis; LN, lymph node.