Table 3.

Classification performance of wavelength subregions of HSI for the detection of head and neck cancer with intrapatient classification and interpatient classification

Primary site	Classification method	Wavelength range (nm)	AUC	Accuracy	Sensitivity	Specificity
Oral cavity	Intrapatient classification	450–600	0.87 ± 0.11	82% ± 11%	81% ± 13%	82% ± 10%
		605–850	0.89 ± 0.12	84% ± 12%	83% ± 12%	85% ± 12%
		855–900	0.76 ± 0.14	72% ± 11%	73% ± 11%	71% ± 12%
		450–900	0.95 ± 0.05	89% ± 8%	90% ± 7%	90% ± 8%
	Interpatient classification	450–600	0.88 ± 0.12	82% ± 11%	82% ± 11%	81% ± 12%
		605–850	0.82 ± 0.11	77% ± 11%	78% ± 10%	76% ± 12%
		855–900	0.71 ± 0.11	67% ± 9%	67% ± 9%	66% ± 11%
		450–900	0.91 ± 0.10	85% ± 10%	85% ± 9%	84% ± 12%
Thyroid	Intrapatient classification	450–600	0.97 ± 0.06	93% ± 8%	93% ± 9%	95% ± 6%
		605–850	0.95 ± 0.06	91% ± 9%	90% ± 10%	92% ± 7%
		855–900	0.93 ± 0.09	89% ± 10%	88% ± 12%	90% ± 8%
		450–900	0.96 ± 0.05	92% ± 7%	92% ± 9%	94% ± 6%
	Interpatient classification	450–600	0.92 ± 0.07	87% ± 9%	86% ± 9%	88% ± 9%
		605–850	0.94 ± 0.05	88% ± 6%	88% ± 6%	88% ± 6%
		855–900	0.84 ± 0.11	78% ± 11%	77% ± 10%	79% ± 10%
		450–900	0.91 ± 0.09	86% ± 10%	85% ± 11%	87% ± 9%