FLG |
Filaggrin |
2312 |
5.8937 |
1.86×10−47
|
1.44×10−44
|
RBP2 |
Retinol binding protein 2 |
5948 |
5.4607 |
3.51×10−25
|
1.75×10−23
|
AQP10 |
Aquaporin 10 |
89872 |
5.4469 |
2.55×10−32
|
3.28×10−30
|
MEP1B |
Meprin A subunit β |
4225 |
5.4444 |
8.12×10−29
|
6.53×10−27
|
SYNPO2L |
Synaptopodin 2-like |
79933 |
4.7689 |
9.87×10−48
|
8.23×10−45
|
MAL |
Mal T-cell differentiation protein |
4118 |
4.5980 |
8.80×10−22
|
3.06×10−20
|
ALOX12 |
Arachidonate 12-lipoxygenase, 12S type |
239 |
4.5728 |
2.61×10−37
|
6.21×10−35
|
ENPP3 |
Ectonucleotide pyrophosphatase/phosphodiesterase 3 |
5169 |
4.5383 |
1.52×10−34
|
2.43×10−32
|
TGM3 |
Transglutaminase 3 |
7053 |
4.4663 |
3.68×10−16
|
5.66×10−15
|
ENDOU |
Endonuclease, poly(U) specific |
8909 |
4.4587 |
9.78×10−19
|
2.17×10−17
|
|
B, Downregulated mRNAs |
|
Gene symbol |
Gene name |
Gene ID |
log2 fold change |
P-value |
False discovery rate |
|
CST1 |
Cystatin SN |
1469 |
−7.4241 |
1.90×10−99
|
1.58×10−95
|
COL10A1 |
Collagen type-X α 1 chain |
1300 |
−7.0398 |
5.07×10−104
|
8.45×10−100
|
ALPP |
Alkaline phosphatase, placental |
250 |
−6.7971 |
1.35×10−42
|
6.25×10−40
|
COL11A1 |
Collagen type-XI α 1 chain |
1301 |
−6.7034 |
2.41×10−70
|
1.00×10−66
|
IBSP |
Integrin-binding sialoprotein |
3381 |
−6.3919 |
4.7×10−40
|
1.70×10−37
|
HOXC10 |
Homeobox C10 |
3226 |
−6.3265 |
7.66×10−59
|
1.60×10−55
|
BAAT |
Bile acid-CoA:amino acid N-acyltransferase |
570 |
−5.8683 |
1.30×10−43
|
6.97×10−41
|
CST4 |
Cystatin S |
1472 |
−5.8488 |
5.52×10−42
|
2.36×10−39
|
PRAME |
Preferentially expressed antigen in melanoma |
23532 |
−5.8100 |
3.13×10−37
|
7.30×10−35
|
IGF2BP1 |
Insulin like growth factor 2 mRNA binding protein 1 |
10642 |
−5.4442 |
5.02×10−29
|
4.08×10−27
|