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. 2017 Aug 23;14(4):4563–4572. doi: 10.3892/ol.2017.6792

Table III.

The top 10 upregulated and downregulated differentially expressed mRNAs in stomach adenocarcinoma.

A, Upregulated mRNAs

Gene symbol Gene name Gene ID log2 fold change P-value False discovery rate
FLG Filaggrin 2312 5.8937 1.86×10−47 1.44×10−44
RBP2 Retinol binding protein 2 5948 5.4607 3.51×10−25 1.75×10−23
AQP10 Aquaporin 10 89872 5.4469 2.55×10−32 3.28×10−30
MEP1B Meprin A subunit β 4225 5.4444 8.12×10−29 6.53×10−27
SYNPO2L Synaptopodin 2-like 79933 4.7689 9.87×10−48 8.23×10−45
MAL Mal T-cell differentiation protein 4118 4.5980 8.80×10−22 3.06×10−20
ALOX12 Arachidonate 12-lipoxygenase, 12S type 239 4.5728 2.61×10−37 6.21×10−35
ENPP3 Ectonucleotide pyrophosphatase/phosphodiesterase 3 5169 4.5383 1.52×10−34 2.43×10−32
TGM3 Transglutaminase 3 7053 4.4663 3.68×10−16 5.66×10−15
ENDOU Endonuclease, poly(U) specific 8909 4.4587 9.78×10−19 2.17×10−17

B, Downregulated mRNAs

Gene symbol Gene name Gene ID log2 fold change P-value False discovery rate

CST1 Cystatin SN 1469 −7.4241 1.90×10−99 1.58×10−95
COL10A1 Collagen type-X α 1 chain 1300 −7.0398 5.07×10−104 8.45×10−100
ALPP Alkaline phosphatase, placental 250 −6.7971 1.35×10−42 6.25×10−40
COL11A1 Collagen type-XI α 1 chain 1301 −6.7034 2.41×10−70 1.00×10−66
IBSP Integrin-binding sialoprotein 3381 −6.3919 4.7×10−40 1.70×10−37
HOXC10 Homeobox C10 3226 −6.3265 7.66×10−59 1.60×10−55
BAAT Bile acid-CoA:amino acid N-acyltransferase 570 −5.8683 1.30×10−43 6.97×10−41
CST4 Cystatin S 1472 −5.8488 5.52×10−42 2.36×10−39
PRAME Preferentially expressed antigen in melanoma 23532 −5.8100 3.13×10−37 7.30×10−35
IGF2BP1 Insulin like growth factor 2 mRNA binding protein 1 10642 −5.4442 5.02×10−29 4.08×10−27