Table 6. Association of H-RAS T81C Polymorphism With the Clinicopathological Features.
Clinical features | No. | TT | CT | CC | P value |
---|---|---|---|---|---|
Patients | 100 | 38 | 61 | 1 | < 0.0001 |
Controls | 100 | 92 | 8 | 0 | |
Males | 65 | 25 | 39 | 1 | < 0.7 |
Female | 35 | 13 | 22 | 0 | |
CP-CML | 50 | 29 | 20 | 1 | < 0.0003 |
AP-CML | 25 | 7 | 18 | 0 | |
BC-CML | 25 | 2 | 23 | 0 | |
A2b2 | 31 | 13 | 18 | 0 | < 0.9 |
A2b3 | 67 | 24 | 42 | 1 | |
A2b2/A2b3 | 2 | 1 | 1 | 0 | |
Imatinib | 100 | 38 | 61 | 1 | |
MMR | 52 | 31 | 21 | 0 | < 0.0001 |
No MR | 48 | 7 | 40 | 1 | |
MHR | 50 | 26 | 24 | 0 | < 0.04 |
Minor HR | 10 | 3 | 7 | 0 | |
Loss HR | 40 | 9 | 30 | 1 | |
Age > 45 | 36 | 11 | 24 | 1 | < 0.2 |
Age ≤ 45 | 64 | 27 | 37 | 0 | |
Thrombocytopenia | 50 | 11 | 38 | 1 | < 0.003 |
No thrombocytopenia | 50 | 27 | 23 | 0 |