Table 3. Immunohistochemical Staining and Clinical Data Association.
Clinical data | N | COX-1 area expression; N (%) |
p | COX-2 area expression; N (%) |
p | ||
---|---|---|---|---|---|---|---|
≤ 75% n = 60 |
> 75% n = 47 |
≤ 75% n = 33 |
> 75% n = 74 |
||||
Age | |||||||
≤ 60 years | 79 | 47 (59.5) | 32 (40.5) | 0.23 | 28 (35.4) | 51 (64.6) | 0.08 |
> 60 years | 28 | 13 (46.4) | 15 (53.6) | 5 (17.9) | 23 (82.1) | ||
Menopausal status | |||||||
premenopause | 51 | 28 (54.9) | 23 (45.1) | 0.82 | 16 (31.4) | 35 (68.6) | 0.91 |
postmenopause | 56 | 32 (57.1) | 24 (42.9) | 17 (30.4) | 39 (69.6) | ||
Residual tumor | |||||||
no residual tumor | 56 | 31 (55.4) | 25 (44.6) | 0.87 | 20 (35.7) | 36 (64.3) | 0.25 |
residual tumor | 51 | 29 (56.9) | 22 (43.1) | 13 (25.5) | 38 (74.5) | ||
Histology | |||||||
mucinous | 25 | 19 (76.0) | 6 (24.0) | 0.02 | 14 (56.0) | 11 (44.0) | 0.002 |
non-mucinous | 82 | 41 (50.0) | 41 (50.0) | 19 (23.2) | 63 (76.8) | ||
Tumor grade | |||||||
G1-2 | 53 | 31 (58.5) | 22 (41.5) | 0.62 | 21 (39.6) | 32 (60.4) | 0.05 |
G3 | 54 | 29 (53.7) | 25 (46.3) | 12 (22.2) | 42 (77.8) | ||
FIGO Staging | |||||||
stage 1-2 | 54 | 30 (55.6) | 24 (44.4) | 0.91 | 20 (37.0) | 34 (63.0) | 0.16 |
stage 3-4 | 53 | 30 (56.6) | 23 (43.4) | 13 (24.5) | 40 (75.5) | ||
Response to first line | N = 88 | n = 48 | n = 40 | n = 26 | n = 62 | ||
chemotherapy | 0.38 | 0.01 | |||||
response | 55 | 32 (58.2) | 23 (41.8) | 11 (20.0) | 44 (80.0) | ||
no response | 33 | 16 (48.5) | 17 (51.5) | 15 (45.5) | 18 (54.5) |