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. 2010 Feb 1;1(1):19–27. doi: 10.4021/wjon2010.02.190w

Table 3. Immunohistochemical Staining and Clinical Data Association.

Clinical data N COX-1 area expression; N (%)
p COX-2 area expression; N (%)
p
≤ 75%
n = 60
> 75%
n = 47
≤ 75%
n = 33
> 75%
n = 74
Age
  ≤ 60 years 79 47 (59.5) 32 (40.5) 0.23 28 (35.4) 51 (64.6) 0.08
  > 60 years 28 13 (46.4) 15 (53.6) 5 (17.9) 23 (82.1)
Menopausal status
  premenopause 51 28 (54.9) 23 (45.1) 0.82 16 (31.4) 35 (68.6) 0.91
  postmenopause 56 32 (57.1) 24 (42.9) 17 (30.4) 39 (69.6)
Residual tumor
  no residual tumor 56 31 (55.4) 25 (44.6) 0.87 20 (35.7) 36 (64.3) 0.25
  residual tumor 51 29 (56.9) 22 (43.1) 13 (25.5) 38 (74.5)
Histology
  mucinous 25 19 (76.0) 6 (24.0) 0.02 14 (56.0) 11 (44.0) 0.002
  non-mucinous 82 41 (50.0) 41 (50.0) 19 (23.2) 63 (76.8)
Tumor grade
  G1-2 53 31 (58.5) 22 (41.5) 0.62 21 (39.6) 32 (60.4) 0.05
  G3 54 29 (53.7) 25 (46.3) 12 (22.2) 42 (77.8)
FIGO Staging
  stage 1-2 54 30 (55.6) 24 (44.4) 0.91 20 (37.0) 34 (63.0) 0.16
  stage 3-4 53 30 (56.6) 23 (43.4) 13 (24.5) 40 (75.5)
Response to first line N = 88 n = 48 n = 40 n = 26 n = 62
  chemotherapy 0.38 0.01
  response 55 32 (58.2) 23 (41.8) 11 (20.0) 44 (80.0)
  no response 33 16 (48.5) 17 (51.5) 15 (45.5) 18 (54.5)