Table 3. Enhancement Ratios^a Due to Combined Treatment With Nicotinamide, or Mild Temperature Hyperthermia.

	Nicotinamide	Mild temperature hyperthermia
Surviving fraction = 0.03
Total cell population
Without thalidomide	1.25 ± 0.1b	1.15 ± 0.05
With thalidomide (once)	1.25 ± 0.1	1.15 ± 0.05
With thalidomide (twice)	1.05 ± 0.05	1.1 ± 0.05
Net micronucleus frequency = 0.6
Total cell population
Without thalidomide	1.2 ± 0.1	1.05 ± 0.05
With thalidomide (once)	1.3 ± 0.1	1.05 ± 0.05
With thalidomide (twice)	1.05 ± 0.05	1.1 ± 0.05
Quiescent cells
Without thalidomide	1.1 ± 0.05	1.2 ± 0.1
With thalidomide (once)	1.05 ± 0.05	1.15 ± 0.05
With thalidomide (twice)	1.1 ± 0.05	1.2 ± 0.05

^aThe ratio of the dose of radiation necessary to obtain each end-point without nicotinamide or mild temperature hyperthermia to that needed to obtain each end-point with nicotinamide or mild temperature hyperthermia. ^bMean ± standard error (n = 6).