Table 5. The Numbers of Metastases From the Irradiated Tumors That Received Cytotoxic Treatment Producing a Similar Initial Local Effect^a.

	Without thalidomide	With thalidomide (once)	With thalidomide (twice)
Surviving fraction = 0.03
γ-Rays only	14.1 ± 1.4b, c, d, e	12.2 ± 1.3	11.9 ± 1.2
With nicotinamide	13.1 ± 1.3	11.4 ± 1.2c, f	11.3 ± 1.2d, g
With mild temperature hyperthermia	14.1 ± 1.4f, g, h	12.2 ± 1.2	10.6 ± 1.1e, h

^aBased on the data shown in Fig. 4, the estimated numbers of lung metastatic nodules from local tumors that received neutron beam irradiation with or without thalidomide in combination with nicotinamide or mild temperature hyperthermia, which produced an identical surviving fraction of 0.6 as an initial effect on Fig. 1. ^bMean ± standard error (n = 6). ^c-hSignificant differences between two values (P < 0.05).