Table 2. The Effects* of Drugs on Each Endpoint.
| BSH# | BSH-CD** | GPU-201** | |
|---|---|---|---|
| Surviving fraction = 0.3 Total cell population |
|||
| Neutron Beams | 1.4 (1.3-1.5)## | 1.7 (1.5-1.9) | 2.3 (2.1-2.5) |
| γ-Rays | 1.05 (1.0-1.1) | 1.15 (1.0-1.3) | 1.25 (1.1-1.4) |
| Net micronucleus frequency = 0.2 Total cell population |
|||
| Neutron Beams | 1.8 (1.65-1.95) | 2.2 (1.9-2.5) | 3.2 (2.9-3.5) |
| γ-Rays | 1.05 (1.0-1.1) | 1.1 (1.0-1.2) | 1.15 (1.05-1.25) |
| Quiescent cells | |||
| Neutron Beams | 1.5 (1.35-1.65) | 1.5 (1.35-1.65) | 3.2 (2.9-3.5) |
| γ-Rays | 1.0 (1.0-1.1) | 1.05 (1.0-1.1) | 1.1 (1.0-1.2) |
*:The dose of radiation required to obtain each endpoint without a drug in relation to that required to obtain each endpoint with a drug; #: Sodium borocaptate-10B dissolved in physiological (0.9%) saline; **: BSH and GPU-201 dissolved in physiological (0.9%) saline containing 10% 2-hydroxypropyl-β-cyclodextrin (HP-β-CD); ##: Numbers in parentheses are 95% confidence limits, determined using mean values, standard deviations, and the numbers of observations on which the means and standard deviations were based.