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. 2017 Oct 15;196(8):993–1003. doi: 10.1164/rccm.201610-1987OC

Table 5.

Lower Limits of Normal and 95% Confidence Intervals for Spirometry Parameters for Men and Women Aged 45 Years and of Average Height

  Women
Men
LLN (95% CI) Ratio Relative to Mexicans LLN (95% CI) Ratio Relative to Mexicans
FEV1, L
 Central American 2.08 (2.03–2.12) 0.98 2.85 (2.78–2.93) 0.97
 Cuban 2.05 (2.01–2.08) 0.97 2.86 (2.80–2.92) 0.97
 Dominican 1.93 (1.87–1.99) 0.92 2.65 (2.58–2.72) 0.90
 Mexican 2.11 (2.08–2.14) 2.94 (2.88–2.99)
 Puerto Rican 1.95 (1.86–2.03) 0.92 2.70 (2.62–2.78) 0.92
 South American 2.13 (2.07–2.18) 1.01 2.97 (2.89–3.05) 1.01
 Other or mixed 2.04 (1.91–2.18) 0.97 2.89 (2.78–3.01) 0.99
FVC, L
 Central American 2.56 (2.51–2.61) 0.97 3.57 (3.48–3.66) 0.96
 Cuban 2.53 (2.48–2.57) 0.96 3.55 (3.48–3.62) 0.96
 Dominican 2.34 (2.28–2.40) 0.89 3.24 (3.16–3.33) 0.88
 Mexican 2.63 (2.59–2.66) 3.70 (3.64–3.76)
 Puerto Rican 2.41 (2.31–2.51) 0.92 3.37 (3.28–3.47) 0.91
 South American 2.65 (2.58–2.72) 1.01 3.75 (3.65–3.85) 1.01
 Other or mixed 2.50 (2.33–2.67) 0.95 3.52 (3.37–3.68) 0.95
FEV1/FVC ratio, %
 Central American 74.51 (74.00–75.02) 1.01 72.42 (71.61–73.24) 1.01
 Cuban 74.42 (73.92–74.92) 1.01 72.92 (72.34–73.50) 1.01
 Dominican 75.73 (75.05–76.41) 1.03 73.86 (73.00–74.72) 1.03
 Mexican 73.80 (73.45–74.15) 71.84 (71.25–72.43)
 Puerto Rican 74.26 (73.47–75.05) 1.01 72.61 (71.70–73.52) 1.01
 South American 73.85 (73.20–74.50) 1.00 71.64 (70.69–72.59) 1.00
 Other or mixed 75.13 (73.79–76.47) 1.02 74.06 (72.86–75.27) 1.03

Definition of abbreviations: CI = confidence interval; LLN = lower limit of normal; MSE = mean squared error.

LLN was constructed using age = 45, height = 170 cm for men and 156 cm for women.

LLN=(β0+β1Age+β2Age2+β3Height)(1.64MSE). 95% CI = LLN ± 1.96Var(LLN), where Var(LLN)=Var(β0+β1Age+β2Age2+β3Height)+(1.642MSE/2n), derived from the variance/covariance matrix of the regression coefficients and the variance of model MSE.