The metabolic diagram, based on Eme et al. [6], shows all enzymes acquired by Blastocystis from different donors. Those that are shared by several other distantly related protist parasites, the excavates Giardia and Trichomonas, the ichthyosporean Sphaeroforma, and the amoebozoan Entamoeba, are highlighted in yellow and the species where the respective enzyme is found are indicated.