Table 1.

Western Blot Analyses of ISR in Visceral White Adipose Tissue of GADD34 and PERK Transgenic Mice Exposed to IH and RA

	GADD34+/+-RA	GADD34+/+-IH	GADD34−/−-RA	GADD34−/−-IH	PERK+/+-RA	PERK+/+-IH	PERK−/+-RA	PERK−/+-IH
p-eIf2α/eIf2α	0.70 ± 0.05*	1.09 ± 0.08*	0.95 ± 0.1	0.85 ± 0.09	0.42 ± 0.13*	0.68 ± 0.20*	0.44 ± 0.26	0.37 ± 0.28
ATF4	0.84 ± 0.13*	1.13 ± 0.17*	0.91 ± 0.07*	0.58 ± 0.024*	0.59 ± 0.028*	1.09 ± 0.13*	0.50 ± 0.07	0.53 ± 0.15

Definition of abbreviations: ATF4, activating transcription factor 4; IH, intermittent hypoxia; ISR, integrated stress response; PERK, PKR-like endoplasmic reticulum kinase; RA, room air.

^*P < 0.05 IH versus RA.