. Author manuscript; available in PMC: 2018 Oct 1.

Published in final edited form as: JAMA Dermatol. 2017 Oct 1;153(10):1026–1031. doi: 10.1001/jamadermatol.2017.2444

Table 3.

Association of Histopathologic Pigmentation Between Incident and Prior Melanomas in 527 Multiple Primary Melanoma Patients in the GEM Study^a

	Incident Primary Melanoma
	Pigmented Melanoma	Amelanotic Melanoma	Amelanotic vs. Pigmented Prior Primary Melanoma
Prior Primary Melanoma	n (%)^b	n (%)^b	OR (95%CI)	P Value^c
Pigmented Melanoma	476 (94.6)	19 (79.2)	1 [Reference]	0.01
Amelanotic Melanoma	27 (5.4)	5 (20.8)	4.62 (1.25–14.13)

Abbreviations: CI, confidence interval; OR, odds ratio.

Includes only patients with second or higher order primary melanomas scored for histopathologic pigmentation

Data are given as number (percentage) of melanomas.

P value was calculated using an exact logistic regression model.