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. 2017 Oct 20;12(10):e0184566. doi: 10.1371/journal.pone.0184566

Table 3. Associations between differentially expressed cytokines, cytokine module, and DC1.

    β 95% CI R2 F P ANCOVA P
IL-2             0.006
  Control 0.43 0.190–0.668 0.862 24.89 0.008  
  Asthma Pre-FP -0.373 -0.661–0.084 0.424 8.093 0.016  
  Asthma Post-FP -0.208 -0.833–0.418 0.059 0.563 0.472  
IL-10             0.508
  Control -0.845 -3.887–2.197 0.129 0.594 0.484  
  Asthma Pre-FP -0.615 -2.158–0.928 0.065 0.77 0.399  
  Asthma Post-FP -2.264 -4.113–0.415 0.46 7.676 0.022  
IL-17F             0.341
  Control 2.351 -11.17–15.87 0.055 0.233 0.655  
  Asthma Pre-FP 8.42 3.323–13.520 0.546 13.22 0.004  
  Asthma Post-FP -1.021 -19.65–17.61 0.002 0.015 0.904  
G-CSF             0.096
  Control -8.322 -31.53–14.89 0.199 0.991 0.376  
  Asthma Pre-FP 11.31 0.525–22.090 0.326 5.328 0.041  
  Asthma Post-FP 4.603 -14.29–23.5 0.033 0.304 0.595  
IFN-γ             0.03
  Control -3.614 -11.56–4.327 0.285 1.596 0.275  
  Asthma Pre-FP 4.008 1.103–6.914 0.456 9.219 0.011  
  Asthma Post-FP 2.421 -4.196–9.037 0.071 0.685 0.429  
MIP-1β             0.058
  Control -1.668 -4.303–0.967 0.436 3.087 0.154  
  Asthma Pre-FP 5.774 0.608–10.940 0.355 6.053 0.032  
  Asthma Post-FP 1.295 -1.119–3.708 0.141 1.472 0.256  
TNF-α             0.002
  Control -0.143 -0.708–0.422 0.11 0.496 0.52  
  Asthma Pre-FP 0.478 0.257–0.699 0.673 22.66 0.001  
  Asthma Post-FP -0.051 -0.288–0.187 0.025 0.234 0.64  
Eigen Value Module 1*             0.007
  Control -0.797 -1.151–0.443 0.907 39.13 0.003  
  Asthma Pre-FP 1.85 0.601–1.028 0.492 10.63 0.008  
  Asthma Post-FP 1.001 -0.035–2.036 0.347 4.779 0.057  
Eigen Value Module 2*             0.078
  Control 1.256 -1.017–3.528 0.37 2.352 0.199  
  Asthma Pre-FP -0.892 -2.066–0.281 0.203 2.801 0.122  
  Asthma Post-FP -0.32 -2.225–1.585 0.016 0.145 0.713  

*Eigen Value Module 1 determined by abundances of IL-1β, IL-8, IL-31, G-CSF, TNF-α, and MIP-1β. Eigen Value Module 2 determined by abundances of IL-17F, IL-21, IL-22, IL-25, sCD40L, and IFN-γ.