Table 3. Associations between differentially expressed cytokines, cytokine module, and DC1.
β | 95% CI | R2 | F | P | ANCOVA P | ||
---|---|---|---|---|---|---|---|
IL-2 | 0.006 | ||||||
Control | 0.43 | 0.190–0.668 | 0.862 | 24.89 | 0.008 | ||
Asthma Pre-FP | -0.373 | -0.661–0.084 | 0.424 | 8.093 | 0.016 | ||
Asthma Post-FP | -0.208 | -0.833–0.418 | 0.059 | 0.563 | 0.472 | ||
IL-10 | 0.508 | ||||||
Control | -0.845 | -3.887–2.197 | 0.129 | 0.594 | 0.484 | ||
Asthma Pre-FP | -0.615 | -2.158–0.928 | 0.065 | 0.77 | 0.399 | ||
Asthma Post-FP | -2.264 | -4.113–0.415 | 0.46 | 7.676 | 0.022 | ||
IL-17F | 0.341 | ||||||
Control | 2.351 | -11.17–15.87 | 0.055 | 0.233 | 0.655 | ||
Asthma Pre-FP | 8.42 | 3.323–13.520 | 0.546 | 13.22 | 0.004 | ||
Asthma Post-FP | -1.021 | -19.65–17.61 | 0.002 | 0.015 | 0.904 | ||
G-CSF | 0.096 | ||||||
Control | -8.322 | -31.53–14.89 | 0.199 | 0.991 | 0.376 | ||
Asthma Pre-FP | 11.31 | 0.525–22.090 | 0.326 | 5.328 | 0.041 | ||
Asthma Post-FP | 4.603 | -14.29–23.5 | 0.033 | 0.304 | 0.595 | ||
IFN-γ | 0.03 | ||||||
Control | -3.614 | -11.56–4.327 | 0.285 | 1.596 | 0.275 | ||
Asthma Pre-FP | 4.008 | 1.103–6.914 | 0.456 | 9.219 | 0.011 | ||
Asthma Post-FP | 2.421 | -4.196–9.037 | 0.071 | 0.685 | 0.429 | ||
MIP-1β | 0.058 | ||||||
Control | -1.668 | -4.303–0.967 | 0.436 | 3.087 | 0.154 | ||
Asthma Pre-FP | 5.774 | 0.608–10.940 | 0.355 | 6.053 | 0.032 | ||
Asthma Post-FP | 1.295 | -1.119–3.708 | 0.141 | 1.472 | 0.256 | ||
TNF-α | 0.002 | ||||||
Control | -0.143 | -0.708–0.422 | 0.11 | 0.496 | 0.52 | ||
Asthma Pre-FP | 0.478 | 0.257–0.699 | 0.673 | 22.66 | 0.001 | ||
Asthma Post-FP | -0.051 | -0.288–0.187 | 0.025 | 0.234 | 0.64 | ||
Eigen Value Module 1* | 0.007 | ||||||
Control | -0.797 | -1.151–0.443 | 0.907 | 39.13 | 0.003 | ||
Asthma Pre-FP | 1.85 | 0.601–1.028 | 0.492 | 10.63 | 0.008 | ||
Asthma Post-FP | 1.001 | -0.035–2.036 | 0.347 | 4.779 | 0.057 | ||
Eigen Value Module 2* | 0.078 | ||||||
Control | 1.256 | -1.017–3.528 | 0.37 | 2.352 | 0.199 | ||
Asthma Pre-FP | -0.892 | -2.066–0.281 | 0.203 | 2.801 | 0.122 | ||
Asthma Post-FP | -0.32 | -2.225–1.585 | 0.016 | 0.145 | 0.713 |
*Eigen Value Module 1 determined by abundances of IL-1β, IL-8, IL-31, G-CSF, TNF-α, and MIP-1β. Eigen Value Module 2 determined by abundances of IL-17F, IL-21, IL-22, IL-25, sCD40L, and IFN-γ.