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. 2017 Oct 20;12(10):e0185716. doi: 10.1371/journal.pone.0185716

Fig 6. Picrosirius red-stained histology under polarized light showed birefringent features associated with collagen fibers.

Fig 6

Discectomy samples show collagen organization in vertebrae, with no tissue in the intervertebral space. Adjacent motion segments show the absence of collagen fibers in the NP and large collagen fibers (~50–100 μm) inserting from the AF to the vertebral body (VB). At 16 weeks, TE-IVD samples show the presence of some small, unorganized collagen fibers in the NP, with larger (~20–50 μm) fibers that insert into the vertebral body (VB).