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. 2017 Oct 20;12(10):e0185600. doi: 10.1371/journal.pone.0185600

Fig 2. High glucose augments AGT secretion of HK-2 cells.

Fig 2

Levels of secreted AGT in the culture medium of HK-2 cells respectively treated with normal glucose (5.5 mM), high glucose (15.0 mM) and normal glucose plus 9.5 mM mannitol. Compared with normal glucose treatment, high glucose significantly augmented AGT secretion into the medium, which was not affected by mannitol-induced osmotic stress. Data are expressed as relative values normalized by total cellular protein amount in the dish. Values are presented as mean ± SEM. *P<0.05 vs. normal glucose group. N = 3~6.