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. 2017 Jul 27;8(43):73372–73386. doi: 10.18632/oncotarget.19637

Figure 8. LSD1 inhibition restores dimethylation and inhibits clonogenic survival of non-metastatic CAL-27 and metastatic HSC-3 cells in vitro.

Figure 8

A. Clonogenic survival was inhibited more than 70% in HSC-3 and CAL-27 cells treated with GSK-LSD1 and B. GSK-LSD1 reduced LSD1 protein expression and restored dimethylation of histone H3 (H3K4me2). Statistical analyses were performed with unpaired Student’s t-tests. The significant differences are indicated with * or # P-value<0.05 in respective groups.